Finally we are in our prime and we really enjoy our stage in life. But the years tend to accumulate and along comes middle age. Finally, we encounter the half-century mark. Now we begin to have some thoughts about aging. Our bodies just don't seem to provide the same amount of physical ability we used to have. And when we look in the mirror we begin to ask who is that looking back at me?
Curcumin: Aging Brains and Cancer
Recent findings show curcumin favorably affects deadly mechanisms involved in cancer and Alzheimer’s, such as impaired cell signaling and abnormal gene regulation. Scientists have also discovered curcumin can boost production of new neurons. Read about: The Aging Brain-Alzheimer's- Parkinson-curcumin & cancer-slow progression of fast growing cancers. READ THE COMPLETE ARTICLE. |
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Protection from DNA Damage and More
Degenerative aging is the result of the accumulation of pathological processes inflicted on cells, tissues, and organs. By targeting each of these degenerative processes, premature aging can be slowed and life span prolonged.Green tea protects against many age-accelerating factors, particularly DNA damage, while also promoting DNA repair. These systems work with extreme precision to identify, remove, and heal damaged DNA. READ THE COMPLETE ARTICLE The Most Sought-After Anti-Aging Drug
Back in the 1980s-1990s, Life Extension® battled the FDA to approve a European drug called deprenyl. The reason we fought so hard was because deprenyl studies showed remarkable longevity benefits in animals and elevations of “feel-good” dopamine in humans. The FDA finally approved deprenyl, but only for treating Parkinson’s disease. For those unable to obtain a deprenyl prescription, compelling research shows that a novel green oat extract exerts the same mechanism as deprenyl to preserve brain dopamine levels. Clinical studies show how this green oat extract can improve blood flow to the brain and cognitive function. READ THE COMPLETE ARTICLE |
AGE RELATED COGNITIVE DECLINE
Press Release: University of California – Los Angeles, January 23, 2018. Lovers of Indian food, give yourselves a second helping: Daily consumption of a certain form of curcumin — the substance that gives Indian curry its bright color — improved memory and mood in people with mild, age-related memory loss, according to the results of a study conducted by UCLA researchers. The research, published online Jan. 19 in the American Journal of Geriatric Psychiatry, examined the effects of an easily absorbed curcumin supplement on memory performance in people without dementia, as well as curcumin’s potential impact on the microscopic plaques and tangles in the brains of people with Alzheimer’s disease. Found in turmeric, curcumin has previously been shown to have anti-inflammatory and antioxidant properties in lab studies. It also has been suggested as a possible reason that senior citizens in India, where curcumin is a dietary staple, have a lower prevalence of Alzheimer’s disease and better cognitive performance. “Exactly how curcumin exerts its effects is not certain, but it may be due to its ability to reduce brain inflammation, which has been linked to both Alzheimer’s disease and major depression,” said Dr. Gary Small, director of geriatric psychiatry at UCLA’s Longevity Center and of the geriatric psychiatry division at the Semel Institute for Neuroscience and Human Behavior at UCLA, and the study’s first author. The double-blind, placebo-controlled study involved 40 adults between the ages of 50 and 90 years who had mild memory complaints. Participants were randomly assigned to receive either a placebo or 90 milligrams of curcumin twice daily for 18 months. All 40 subjects received standardized cognitive assessments at the start of the study and at six-month intervals, and monitoring of curcumin levels in their blood at the start of the study and after 18 months. Thirty of the volunteers underwent positron emission tomography, or PET scans, to determine the levels of amyloid and tau in their brains at the start of the study and after 18 months. The people who took curcumin experienced significant improvements in their memory and attention abilities, while the subjects who received placebo did not, Small said. In memory tests, the people taking curcumin improved by 28 percent over the 18 months. Those taking curcumin also had mild improvements in mood, and their brain PET scans showed significantly less amyloid and tau signals in the amygdala and hypothalamus than those who took placebos. The amygdala and hypothalamus are regions of the brain that control several memory and emotional functions. Four people taking curcumin, and two taking placebos, experienced mild side effects such as abdominal pain and nausea. The researchers plan to conduct a follow-up study with a larger number of people. That study will include some people with mild depression so the scientists can explore whether curcumin also has antidepressant effects. The larger sample also would allow them to analyze whether curcumin’s memory-enhancing effects vary according to people’s genetic risk for Alzheimer’s, their age or the extent of their cognitive problems. “These results suggest that taking this relatively safe form of curcumin could provide meaningful cognitive benefits over the years,” said Small, UCLA’s Parlow-Solomon Professor on Aging. Journal Reference: Gary W. Small, Prabha Siddarth, Zhaoping Li, Karen J. Miller, Linda Ercoli, Natacha D. Emerson, Jacqueline Martinez, Koon-Pong Wong, Jie Liu, David A. Merrill, Stephen T. Chen, Susanne M. Henning, Nagichettiar Satyamurthy, Sung-Cheng Huang, David Heber, Jorge R. Barrio. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial. The American Journal of Geriatric Psychiatry, 2017; DOI: 10.1016/j.jagp.2017.10.010 |
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For anyone with a medical condition, or using prescribed drugs, consult with your health care provider before making any changes in your treatment procedure.
Information on this site should never be considered as a substitute for professional medical advice.
This site only provides information for those who are interested in a med (drug) free life style. By definition, their health must be in a state where prescription drugs are not required. Any substitution for prescription drugs should only be made after consultation with one’s health care provider.
Should anyone have any doubts as to their need for health care advice, one should seek it out without delay.